Shaomeng wang group umichigan

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Webb13 dec. 2024 · Professors Gunda Georg and Shaomeng Wang served as joint Editors-in-Chief of the Journal of Medicinal Chemistry from 2011 to 2024, succeeding Professor … WebbIncluding their publications and grants. Skip to main content. All experts. ABOUTSCHOLARLY ACTIVITIESGRANTS. Shaomeng Wang has not uploaded a photo. …

Shaomeng WANG Professor PhD University of Electronic …

WebbThe natural product-like compound 1 was identified as a direct inhibitor of the menin–MLL interaction by in silico screening. Structure-based optimization furnished analogue 1a, which showed significantly higher potency than both the lead structure 1 and the reference compound MI-2. WebbDr. Wang was named the Warner-Lambert/Parke-Davis Professor in Medicine in 2007. Dr. Wang serves as the Co-Director of the Molecular Therapeutics Program at the University … simplify 12/39

Wang Lab - Chemistry lab - University of Michigan

WebbShaomeng Wang is a co-founder of Ascenta and is currently the Warner-Lambert/Parke-Davis Professor in Medicine at the University of Michigan Medical School and professor of medicinal chemistry, internal medicine and pharmacology at the University of Michigan. Shaomeng Wang received his B.S. in Chemistry from Peking University in 1986 and his … WebbDr. Wang was named the Warner-Lambert/Parke-Davis Professor in Medicine in 2007. Dr. Wang serves as the Co-Director of the Molecular Therapeutics Program at the University … WebbDr. Shaomeng Wang has b een working on the discovery and development of novel small molecules therapeutics for more than 20 years. One area of research has been focused … simplify 12/42

Wang Lab - Open positions - University of Michigan

Wang Lab - Publications - University of Michigan

WebbThis patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results. WebbAfter spending one year as a Postdoctoral Research Fellow at Purdue University, USA, he joined the Wang Lab in 2016. Currently focused on the development of novel small molecule inhibitors (EED/LSD1) and drug-like properties for optimization of PROTACs. Lingying Yeng Research Fellow [email protected] Ph.D. Sichuan University, China … simplify 12/40Webb13 dec. 2024 · Professor Shaomeng Wang’s Research Highlights. Shaomeng published his ﬁrst paper in J. Med. Chem. in 1994,17 which focused on modeling the binding site of … raymond pierson

"WebbShaomeng Wang is a Chinese-American chemist currently the Warner-Lambert/Parke-Davis Professor in Medicine at University of Michigan [1] and a former Co-Editor-in-Chief at … " - Shaomeng wang group umichigan

Shaomeng wang group umichigan

Webb4 juli 2024 · Building upon work that led to a pan-BET γ-carboline inhibitor 181, the group of Shaomeng Wang has reported a series of PROTACs that link this compound to imide-based cereblon ligands 182 and ... WebbShaomeng Wang's lab University of Michigan (U-M) Overview Advance your research research projects Featured research (4) Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase...

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Webb1 okt. 2024 · Among them, Shaomeng Wang reported two most potent PROTACs which could degrade proteins when the concentration was only at picomolar level, 11 and 12 (Fig. 3) [40, 41]. 11 could lower levels of BRD3 and BRD4 when the concentration was only at 10 pM, while the expression of BRD2 could be reduced when 11 reached 30–100 pM. 11 … Webb15 maj 2013 · Our study has led to the identification of a set of highly potent MDM2 inhibitors with a stereochemistry that is different from that of our previously reported compounds. The most potent compound (MI-888) binds to MDM2 with a Ki value of 0.44 nM and achieves complete and long-lasting tumor regression in an animal model of …

Webb27 okt. 2024 · The bicyclic aromatic group of DI-591 is buried in a deep hydrophobic pocket defined by I86, F89, C90, F109, ... Haibin Zhou, Jianfeng Lu, Liu Liu, Denzil Bernard, Chao-Yie Yang & Shaomeng Wang. Webb18 feb. 2024 · Since 2002, he has submitted 111 inventions to U-M’s Office of Technology Transfer, executed 63 commercialization agreements, and founded five startups. His …

WebbFormer Group Members _____ Name Current (or last ... (Prof. Shaomeng Wang) Jeremy Fournier Scientist, Arcus Biosciences, Hayward, CA. Kyle Young Scientist, Boehringer Ingelheim, Germany. Joseph Alvarado ... WebbAdministrative Assistant, Senior . [email protected]. Nicholas VanDyke. Lab Manager. [email protected]

WebbWang is also on the board of Ascentage Pharma Group International Co., Ltd., Oncopia Therapeutics, Inc., Rogel Cancer Center: University of Michigan and Ascentage International Ltd. Shao Meng Wang previously held the position of Editor-in-Chief at Journal of Medicinal Chemistry, Professor at the University of Michigan, Assistant Professor at Georgetown …

Webb1 nov. 2024 · Shaomeng Wang, Ph.D. Warner-Lambert/Parke-Davis Professor in Medicine. Professor of Medicine, Pharmacology and Medicinal Chemistry. Director, Cancer Drug … simplify 126/300Webb1 nov. 2024 · Guo G, Li X, Wang Q, Li Y, Chu H, Ma Q, Tu J, Zhang D. IEEE Trans Ultrason Ferroelectr Freq Control, 68(4):1399-1407, 26 Mar 2024 Cited by: 0 articles PMID: 33108285. Polarization-Encrypted Orbital Angular Momentum ... Europe PMC is a service of the Europe PMC Funders' Group, ... simplify 125 -1/3WebbShaomeng Wang. University of Michigan. Verified email at umich.edu ... Computer automated log P calculations based on an extended group contribution approach. G … raymond pierce sefWebbAfter spending one year as a Postdoctoral Research Fellow at Purdue University, USA, he joined the Wang Lab in 2016. Currently focused on the development of novel small … simplify 1/27 -2/3Webb13 dec. 2024 · Shaomeng Wang and Gunda I. Georg J. Med. Chem.2012,55,1,1-1 Publication Date(Web):December 22, 2011 Full Text PDF Synthesis of biologically active taxol analogs with modified phenylisoserine side chains Gunda I. Georg, Zacharia S. Cheruvallath, Richard H. Himes, Magdalena R. Mejillano, and Charles T. Burke J. Med. … simplify 1/2 4WebbWang LD, Shaomeng Wang and Sun D. Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling of an Antagonist (SM406/AT-406) of Multiple Inhibitor of … simplify 12/48 to its simplest form [email protected] didates for further experimental characterization. The basic assumption underlying structure-based drug de-sign is that a good ligand molecule should bind tightly to its target. simplify 125/1296