WebMar 15, 2013 · We retrospectively evaluated the effectiveness and safety of high-dose daptomycin (HD-daptomycin) therapy (>6 mg/kg) in a multicenter cohort of adult patients with enterococcal infections to describe the characteristics and outcomes. Two hundred forty-five patients were evaluated. WebJul 1, 2014 · Daptomycin is a cyclic lipopeptide antibiotic with rapid, concentration-dependent bactericidal activity in vitro against relevant gram-positive organisms such as Staphylococcus aureus and enterococci. 1,–4 Daptomycin 4 or 6 mg/kg once daily is indicated for the treatment of patients with normal renal function who have complicated …
Effect of Statin Coadministration on the Risk of Daptomycin …
WebDec 11, 2024 · Daptomycin is associated with an increased incidence of myopathy and rhabdomyolysis. There have been cases reported in patients with and without acute … Webelevated CPK, and hypertension. (6.1) Pediatric S. aureus bacteremia Patients: The most common adverse reactions that occurred in ≥5% of pediatric patients receiving CUBICIN were vomiting and elevated CPK. (6.1) To report SUSPECTED ADVERSE REACTIONS, contact Merck Sharp & Dohme LLC at 1-877-888-4231 or FDA at 1-800-FDA-1088 north andover ma 586 mass ave
Effect of Statin Coadministration on the Risk of Daptomycin
WebApr 5, 2024 · Cubicin RF (Daptomycin Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. ... Table 9: … WebDec 19, 2024 · Those with CPK >2000 U/L were defined as having rhabdomyolysis. These cases were matched to controls receiving daptomycin but without CPK elevations. Among 3042 patients receiving daptomycin, 128 (4.2%) were defined as having daptomycin-associated myopathy and 25 (0.8%) having rhabdomyolysis. WebNov 23, 2024 · Daptomycin will not treat a viral infection such as the flu or a common cold. Store daptomycin in the refrigerator. Do not freeze. After mixing daptomycin with a diluent, store in the refrigerator and use it within 48 hours. You may also store mixed daptomycin for up to 12 hours at room temperature. Each vial (bottle) is for one use only. north andover lake cochichewick