Ctbp ogdhl

WebDec 23, 2016 · An international team of scientists has discovered that the gene OGDHL, or oxoglutarate dehydrogenase-like, which encodes a key protein required for normal function of the mitochondria, and its... WebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase ( EC 1.2.4.2) for reduction of protein-bound lipoyl groups ( Bunik and Degtyarev, 2008 ). OGDHL encodes a rate-limiting enzyme in the Krebs cycle that plays a pivotal role in mitochondrial metabolism ( Yap et al., 2024 ). Cloning and Expression

CBP DTOPS

WebConclusion: Our findings established that silencing of OGDHL contributed to HCC development and survival by regulating glutamine metabolic pathways. OGDHL is a … WebApr 9, 2024 · CtBP_dh; C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor; NM_001377187.1 → NP_001364116.1 C-terminal-binding protein 1 isoform 4. Status: REVIEWED. Source sequence(s) AC092535 Consensus CDS CCDS93461.1 UniProtKB/TrEMBL H0Y8U5 Conserved Domains (1) summary … diamond right hand rings for women https://sean-stewart.org

OGDHL Gene - GeneCards OGDHL Protein OGDHL Antibody

WebAug 5, 2024 · OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism. OGDHL closely associates with tumor microenvironment and can … WebAug 5, 2024 · Gene ID: 55753, updated on 5-Aug-2024 Summary The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glucose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. The CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional corepressors. That is, regulatory proteins that bind to sequence-specific DNA-binding proteins and help turn genes off. CtBPs do this by recruiting histone modifying enzymes that add repressive histone marks and remove activating marks. CtBP proteins can also self-as… diamond ridge townhomes woodlawn md

OGDHL Gene - GeneCards OGDHL Protein OGDHL Antibody

Category:VCV000402144.3 - ClinVar - NCBI

Tags:Ctbp ogdhl

Ctbp ogdhl

DHS

WebJan 12, 2024 · OGDHL is predicted to be a thiamine diphosphate-dependent 2-oxo acid dehydrogenase (EC 1.2.4.2) for reduction of protein-bound lipoyl groups (Bunik and … http://www.ctbtrucks.com/

Ctbp ogdhl

Did you know?

WebThe overexpression of OGDHL also markedly suppressed the growth of HCC-LM3/OGDHL xenograft tumors in immunodeficient mice (p = 0.014; Figure 8C,D); these findings were … Web17110-1-AP targets OGDHL in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH …

WebCBP appreciates your assistance in strengthening global supply chain security and commitment to trade compliance. As you begin your application for CBP's Trusted … WebOgdhl: Name: oxoglutarate dehydrogenase L: RGD ID: 1310916: Description: Predicted to enable oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in 2-oxoglutarate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrial matrix. Predicted to be part of oxoglutarate dehydrogenase complex.

WebOGDHL has 3,312 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 66 datasets. Click the + buttons to view associations for ... WebAug 14, 2015 · The OGDHL promoter methylation pattern was assumed to provide a marker for differential diagnosis of CIMP+ (CpG island methylator phenotype) tumors, which display dense hypermethylation of the promoter region in many genes. Cell metabolic reprogramming is one of the cancer hallmarks. Glycolysis activation, along with …

WebJul 22, 2024 · Hepatocyte-specific SIRT5 overexpressing mice (liver SIRT5 OE) were generated to address the possible involvement of hepatic SIRT5 in AMI. The areas of myocardial infarction, myocardial fibrosis, and cardiac function in a model of experimental myocardial infarction were compared between liver SIRT5 OE mice and wild-type (WT) …

WebOGDHL (FLJ10851) protein expression summary. The protein encoded by this gene is similar to oxoglutarate dehydrogenase (OGDH) of the OGDH complex, which degrades glu cose and glutamate. This gene encodes several isoforms, including some that appear to localize to mitochondria. diamond ridge townhomes utahWebThe CTP Portal is intended for use by regulated tobacco Industry, including manufacturers, importers, and distributors who make submissions to CTP. The CTP Portal should … diamond ring 1000Web3PL Freight & Shipping Solutions. Coastal Transportation Services Commitment to Excellence means that we deliver personalized service at competitive prices with one … diamond rihanna youtubeWebOct 17, 2024 · Background and Objective . Liver cancer is a highly malignant tumor, and patients typically have poor prognoses. Metabolic reprogramming is a hallmark of cancer, and downregulation of … diamond ring 1920WebJul 31, 2024 · ogdhl沉默后，以αkg依赖性方式激活了mtorc1信号通路 ，从而诱导了在新生脂肪形成中具有关键作用的酶发生转录，进一步说明了ogdhl的功能。 前面的功能实验 … cisco firepower 2010WebMar 21, 2024 · OGDHL (Oxoglutarate Dehydrogenase L) is a Protein Coding gene. Diseases associated with OGDHL include Yoon-Bellen Neurodevelopmental Syndrome … diamond ridge troy ny independent livingWebJan 14, 2024 · In a 15-year-old girl (BAB4852), born of consanguineous Turkish parents, with Yoon-Bellen neurodevelopmental syndrome (YOBELN; 619701), Yoon et al. (2024) identified a homozygous c.2333C-T transition (c.2333C-T, NM_018245) in exon 18 of the OGDHL gene, resulting in a ser778-to-leu (S778L) substitution at a conserved region in … diamond ridge townhomes draper utah